Pain is a feeling that causes great discomfort, especially when it’s severe. We experience it in various occasions, usually due to a disease, an injury or after a medical operation. Very high levels of pain are not only unbearable but may also have negative effects on the person’s functions.
So far, the most common painkiller administered strictly by doctors to patients that are under constant monitoring, is morphine. Even though its effectiveness in neutralizing pain is very high, it is known to have some very serious side effects, some of which may even turn out to be fatal for the user.
Through miracles of modern science, medicine and bio-engineering, we now have a substitute for morphine that is equally efficient and also has a huge advantage over the aforementioned substance. Its name is PZM21.
The creation of PZM21 is the result of extensive studying and trials conducted by an international scientific team that used state of the art technology to be able to make such an amazing invention. The numbers speak for themselves.
Using powerful computers and pieces of software, the team conducted the mind blowing number of 4 trillion virtual simulations before reaching the point of getting the desired result. However, their work was not over. This “result” was not the formula of the drug but instead, a number of molecules that fitted the desired criteria. The final list included 23 “candidates”, 2 of which were eliminated for not fulfilling the desired criteria to the maximum. The one that was chosen went through another round of detailed studying and trials, while an additional stage of “tweaking” increased its already huge effectiveness by 1.000 times. And just like that, the PZM21 was created.
What makes this breakthrough so amazing is the fact that for the first time ever a drug was designed to fit the requirements of its receptor. In our case, it was the morphine (mu-opioid) receptor of the human brain. So far, drugs were designed by taking into account their degree of success in attacking the “target” but now, since we have extensive knowledge of the way many drugs are handled and used by our body, the success rate is greatly increased.
It is certain that we are living in an era of phenomenal inventions and breakthroughs, one that could soon provide us the tools and weapons required to fight and neutralize some of our toughest medical opponents.